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What is Solumedrol?

Solumedrol is an intravenous steroid that helps prevent inflammation. It is used for treating arthritis, lupus, psoriasis, ulcerative colitis, allergic disorders, endocrine disorders, and conditions that affect the skin, eyes, lungs, stomach, nervous system, or blood cells.

What are the most important things I should know about Solumedrol?

Solumedrol is not recommended for patients with fungal infections, a weakened immune system, or patients who are currently taking steroids.

Tell your doctor if you’re pregnant or breastfeeding. It is not known whether Solumedrol could harm your baby.

Avoid being around people who are sick or have infections. Contact your doctor immediately if you have been exposed to chickenpox or measles — such conditions could be fatal for a person using Solumedrol.

Do not receive live vaccines while being treated with Solumedrol — including those for measles, mumps, rubella, rotavirus, typhoid, yellow fever, varicella (chickenpox), shingles, or influenza.

Prior to treatment, tell your doctor if you’ve had a history of any of the following:

  • High blood pressure
  • Heart disease
  • Thyroid disorder
  • Diabetes
  • Glaucoma
  • Cataracts
  • Kidney disease
  • Cirrhosis
  • Liver disease
  • Epilepsy
  • Seizures
  • A recent head injury
  • Tuberculosis
  • Herpes of the eyes
  • Scleroderma
  • Stomach ulcers
  • Ulcerative Colitis
  • Diverticulitis
  • Intestinal surgery
  • Parasite infections
  • Mental illness
  • Osteoporosis
  • Muscle disorders
  • Electrolyte imbalance

What are the common side effects of Solumedrol?

Common side effects of Solumedrol may include:

  • Weight gain
  • Slow wound healing
  • Muscle pain
  • Weakness
  • Thinning skin
  • Increased sweating
  • Bloating
  • Headaches
  • Changes in your menstrual periods

Call your doctor immediately if you experience any of the following side effects:

  • Blurred vision
  • Tunnel vision
  • Eye pain
  • Seeing halos around lights
  • Shortness of breath
  • Swelling
  • Severe depression
  • Changes in personality
  • Pain in arms, legs, or back
  • Severe pain in the upper stomach that spreads to the back
  • Nausea
  • Vomiting
  • Bloody stools
  • Coughing up blood
  • Vomit that looks like coffee grounds
  • Seizures
  • Leg cramps
  • Constipation
  • Irregular heartbeats
  • Increased thirst
  • Increased urination
  • Numbness
  • Tingling
  • Muscle weakness
  • Feeling limp

These are not all of the possible side effects of Solumedrol. Talk to your doctor about any side effects that you experience. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.