Ertapenem (Invanz)
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What is Ertapenem?

Ertapenem (Invanz) is an infusion medication used to treat serious bacterial infections throughout the body by killing off the infection-causing bacteria. It is intended for use in adults and children aged 3 months and older who have moderate to severe infections caused by susceptible bacteria, including:

  • Complicated intra-abdominal infections
  • Complicated skin and skin structure infections
  • Diabetic foot infections without osteomyelitis
  • Community-acquired pneumonia
  • Complicated urinary tract infections
  • Acute pelvic infections
  • Certain post-surgical infections

Important Safety Information

In order to decrease the risk of drug-resistant bacteria, Ertapenem should only be used to treat infections caused by susceptible bacteria. It will not work to fight flu, colds, or any other viral infections.

If you are allergic to certain antibiotics or local anesthetics you should not take Ertapenem.

What is the most important information I should know about Ertapenem?

Before taking Ertapenem tell your doctor if you:

  • Have ever had allergic reactions to Ertapenem, other carbapenem antibiotics, or any local anesthetics.
  • Are taking any other medications, supplements, or herbal products, especially if they contain probenecid or valproic acid
  • Have ever had brain lesions, seizures, or kidney stones
  • Are pregnant, plan to become pregnant, or are breastfeeding


A typical infusion of Ertapenem will last around 30 minutes.


For adults and pediatric patients 13 years and older: 1 gram once a day intravenously or intramuscularly.

For patients 3 months to 12 years of age: 15 mg/kg twice daily (not to exceed 1 g/day) intravenously or intramuscularly.

IV infusion treatments of Ertapenem may be administered in adults and pediatrics for up to 14 days.

Ertapenem Side Effects

Common side effects of Ertapenem in both adults and children include:

  • Diarrhea
  • Nausea
  • Headache
  • IV site reaction
  • Dizziness
  • Stomach pain
  • Fever
  • Cough
  • Confusion
  • Difficulty falling asleep or staying asleep
  • Redness or irritation at the injection site
  • Swelling, redness, burning, itching, or irritation of the vagina
  • Swelling of the hands, feet, ankles, or lower legs

While serious side effects are rare, these may include (but are not limited to):

  • Severe diarrhea (watery or bloody stools) that may occur with or without fever and stomach cramps (may occur up to 2 months or more after your treatment)
  • Hives
  • Rash
  • Itching
  • Difficulty breathing or swallowing
  • Seizures
  • Unusual tiredness or weakness
  • Pale skin
  • Fast or irregular heartbeat
  • Shortness of breath
  • Chest pain

If you are experiencing any of these severe symptoms, discontinue Ertapenem usage and seek emergency medical care.

Tell your doctor if you experience any negative side effects from taking Ertapenem. You are also encouraged to report such side effects to the Food and Drug Administration (FDA) by visiting, or by calling 1-800-FDA-1088.


Ertapenem is indicated for the treatment of adult patients and pediatric patients (3 months of age and older) with the following moderate to severe infections caused by susceptible isolates of the designated microorganisms: Complicated intra-abdominal infections, complicated skin and skin structure infections, community-acquired pneumonia, complicated urinary tract infections acute pelvic infections, and certain post-surgical infections.

Please refer to the full prescribing information.